Bone Loss
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NASA
Risk of Renal Stone Formation
Exposure to microgravity induces bone atrophy/bone loss which increases circulating calcium, impacting the renal stone risk. Risk mitigation strategies including exercise and hydration are well-defined although the ability to treat a renal stone during exploration missions is not yet available. Directed Acyclic Graph Files + DAG File Information (HSRB Home Page) + Risk of Renal Stone Formation DAG and Narrative (PDF) + Risk of…
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NASA
Counteracting Bone and Muscle Loss in Microgravity
In microgravity, without the continuous load of Earth’s gravity, the tissues that make up bones reshape themselves. Bone cells readjust their behaviors—the cells that build new bone slow down, while the cells that break down old or damaged bone tissue keep operating at their normal pace so that breakdown outpaces growth, producing weaker and more brittle bones. For every month…
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