SOMA

NASA

Aging and Fragility Biomarkers are Altered by Spaceflight

Spaceflight accelerates the symptoms of aging in astronaut bodies by inducing genomic instability, mitochondrial dysfunction, and increased inflammation. This is the first study to comprehensively examine biomarkers and pathways associated with spaceflight and terrestrial aging, frailty, and sarcopenia. Main Findings: Spaceflight induced notable changes in gene expression patterns related to frailty and muscle loss indicative of a frailty-like condition. Exposure…